COMORBIDITY & CLL DIFFERENT SCORES – DIFFERENT RESULTS
نویسندگان
چکیده
Introduction: Due to the implementation of outpatient centres, our network provides care for 50% patients with hematological diseases in Vienna. Here we analyse influence own CIRS Score on survival CLL patients. Additionally focus renal comorbidities. Methods: 1150 who were diagnosed, observed and treated between 2011 2021 within haematological analysed. Study data was generated by reviewing electronic paper medical records. Comorbidities assessed conventional including utilizing Version where did not severity detect more We differentiated 2 groups: low risk pts. without any or just one existing co-morbidity high-risk organ systems involved, regardless severity. Moreover demonstrate a Composite Comorbidity “Severe4” <3 >3 points, validated 4 Organ Systems as shown ASH 2022 Shouse et al. cut-off 6 points used German Group. Furthermore Cockcroft-Gault formula (GFR). Results: 55% male. The median age at diagnosis 68 years. IGHV mutated 53% patients, del(17p) present 7,4% 27% received specific treatment. As Figure 1 interpretation CIRS-Score able identify 625 classified high significant lower OS. Regardless Severity, involvement relevant than one. Similarly Severe4 could also show OS difference 167 using 3 Points least category. A highly can be 245 pts when established points. Emphasizing weakness detecting comorbidity due threshold concerning Serum Creatinine 1,5 mg/dl that 144 had GFR <60 mL/min time diagnosis, which reflects Stage CKD, resulting When alone only 31 would have been impaired. Keyword: chronic lymphocytic leukemia (CLL) No conflicts interests pertinent abstract.
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ژورنال
عنوان ژورنال: Hematological Oncology
سال: 2023
ISSN: ['1099-1069', '0278-0232']
DOI: https://doi.org/10.1002/hon.3165_585